Biologic Material for Tissue Regeneration (D4265) — National Rates

Negotiated reimbursement rates for D4265 across 47 states, sourced from CMS Transparency in Coverage data. 710 rate records.

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National Average Negotiated Rate
$292
710 rate records · 47 states
📊 Data updated monthly · Last refresh: March 2026

About D4265 — Biologic Material for Tissue Regeneration

D4265 is used for the application of Biologic Material for Tissue Regeneration. This procedure is clinically indicated when there is a need to promote tissue healing and regeneration, particularly in periodontal therapy. Documentation should include details about the materials used, the sites treated, and the expected outcomes. Reimbursement for this procedure can vary significantly by payor, with some plans offering comprehensive coverage while others may impose restrictions or require additional documentation. The average reimbursement for D4265 is approximately $292, but dental billing professionals should verify coverage specifics with each payor to ensure proper reimbursement.

Reimbursement rates for D4265 vary significantly by state, payor, and provider network. The national average negotiated rate is $292. Data sourced from CMS Transparency in Coverage machine-readable files, updated monthly.

Top Paying States for D4265

New York
$642
30 records
Maine
$420
1 records
Virginia
$410
40 records

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Full National Breakdown

Median
$285
Low
$83
High
$900

Highest & Lowest Reimbursement States

↑ Top 5

StateAvg Rate
New York$642
Maine$420
Virginia$410
New Hampshire$383
Washington$371

↓ Bottom 5

StateAvg Rate
Nevada$202
Delaware$181
North Carolina$178
North Dakota$167
Rhode Island$159

All States — D4265 Average Rates

New York
$642
Maine
$420
Virginia
$410
New Hampshire
$383
Washington
$371
Oregon
$369
District of Columbia
$349
Iowa
$347
Hawaii
$342
Tennessee
$324
Kansas
$322
Louisiana
$322
Michigan
$317
Missouri
$312
Oklahoma
$309
West Virginia
$307
Georgia
$307
Mississippi
$303
Florida
$290
South Dakota
$289
Massachusetts
$284
South Carolina
$279
Kentucky
$272
Texas
$268
Alaska
$262
Wisconsin
$259
California
$258
Pennsylvania
$253
Idaho
$248
Illinois
$246
Minnesota
$238
New Mexico
$235
Ohio
$234
Utah
$233
Nebraska
$228
Colorado
$225
Maryland
$224
Indiana
$218
New Jersey
$218
Connecticut
$217
Arizona
$211
Alabama
$202
Nevada
$202
Delaware
$181
North Carolina
$178
North Dakota
$167
Rhode Island
$159
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State-by-State Comparison Table

StateAverageMedianMinMaxRecords
New York$642$854$146$90030
Maine$420$420$420$4201
Virginia$410$402$154$56640
New Hampshire$383$360$210$4838
Washington$371$433$214$4626
Oregon$369$366$300$4444
District of Columbia$349$400$212$4353
Iowa$347$352$175$47510
Hawaii$342$342$239$4452
Tennessee$324$308$280$4024
Kansas$322$298$282$3589
Louisiana$322$346$181$3468
Michigan$317$325$250$4027
Missouri$312$301$267$39324
Oklahoma$309$309$301$3172
West Virginia$307$315$292$3153
Georgia$307$309$156$37672
Mississippi$303$303$303$3031
Florida$290$285$137$38642
South Dakota$289$289$226$3522
Massachusetts$284$210$137$53519
South Carolina$279$266$156$66733
Kentucky$272$287$160$40215
Texas$268$315$125$39338
Alaska$262$262$262$2623
Wisconsin$259$275$174$2796
California$258$214$123$566117
Pennsylvania$253$220$161$56614
Idaho$248$179$179$3525
Illinois$246$252$137$35210
Minnesota$238$236$137$3403
New Mexico$235$239$222$24710
Ohio$234$196$172$35210
Utah$233$232$209$2584
Nebraska$228$192$137$3526
Colorado$225$209$143$40214
Maryland$224$238$144$2809
Indiana$218$224$150$28716
New Jersey$218$161$123$34017
Connecticut$217$200$200$2845
Arizona$211$227$132$3365
Alabama$202$202$191$2144
Nevada$202$153$137$45718
Delaware$181$181$181$1811
North Carolina$178$163$138$30912
North Dakota$167$137$123$3459
Rhode Island$159$146$146$21010
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